Josephine F Esquivel-Upshaw

Josephine F Esquivel-Upshaw, D.M.D.

Interim Director & Professor, Division of Prosthodontics

Department: DN-PROSTHODONTICS DIVISION
Business Phone: (352) 273-5850
Business Email: jesquivel@dental.ufl.edu

About Josephine F Esquivel-Upshaw

Dr. Esquivel-Upshaw completed her Doctor of Dental Medicine degree from the University of the Philippines in 1991. She completed her residency training in Prosthodontics at Northwestern University in 1994 with a Masters in Advanced Dental Education and a Certificate in Prosthodontics. In 2009 she completed a Masters in Clinical Investigation at the University of Florida College of Medicine. 

Dr. Esquivel-Upshaw started her academic career at the University of Florida College of Dentistry where she worked as a clinical fellow in 1994. She became an Assistant Professor in 1995 and was promoted to Associate Professor with tenure in 2000.  She moved to San Antonio, Texas to work at the University of Texas Health Science Center at San Antonio where she worked in the General Dentistry department as a group practice leader until 2006. She moved back to UF in 2006 as an Associate Professor and was granted tenure again in 2009. She currently works in the Department of Restorative Dental Sciences in the Division of Prosthodontics.

Dr. Esquivel-Upshaw is an active member of the American Association of Dental Research, International Association of Dental Research and the American College of Prosthodontists. She is a journal reviewer for several dental journals including Dental Materials and the Journal of Prosthodontics to name a few. Her patient care activities include fixed and removable denture prostheses mainly for clinical research.

Accomplishments

Fellow
2018 · American College of Dentists
Member
2008 · Omicron Kappa Upsilon Dental Honor Soceity

Teaching Profile

Courses Taught
2014-2015,2018-2022,2020-2025,2022-2025,2024-2025
DEN6412C Preclin Fixed Prost 1
2011-2018,2020-2025
DEN7845L Cl Prosthodontics 1
2016,2020-2022,2022-2025,2024-2025
DEN7411C Implant Dentistry
2008,2011-2015,2015-2023,2020-2025
DEN8858L Clinical Prosthodon 4
2011,2013-2020,2020-2022
DEN7413C Rem Part Pros Techniq
2012-2016,2018-2024,2020-2025
DEN8857L Clinical Prosthodon 3
2015,2020
DEN7961L Clinical Examinaton 1
2019-2020
DEN8960L Clinical Examinatio 2
2011-2014,2020-2025
DEN6973 Project in Lieu of Thesis
2020-2022,2024-2025
DEN6460C Prostho Trtment Edent
2011-2024
DEN7846L Cl Prosthodontics 2
2008,2011-2024
DEN8859L Clinical Prosthodon 5
2012,2020-2025
DEN6910 Supervised Research
2013,2018
DEN8290 Special Topics
2016-2017,2022
DEN6213C Fundamen of Occlusion
2016
DEN6415C Preclin Fixed Prost 2
2023-2025
DEN6940 Supervised Teaching
2023-2024
DEN6508C Essentials of Clinical Care
2024-2025
DEN6971 Research for Master’s Thesis
2024
DEN8462 Adv Top Prosthodontic

Clinical Profile

Dr. Esquivel-Upshaw completed her Doctor of Dental Medicine degree from the University of the Philippines in 1991. She completed her residency training in Prosthodontics at Northwestern University in 1994 with a Masters in Advanced Dental Education and a Certificate in Prosthodontics. In 2009 she completed a Masters in Clinical Investigation at the University of Florida College of Medicine.

Dr. Esquivel-Upshaw started her academic career at the University of Florida College of Dentistry where she worked as a clinical fellow in 1994. She became an Assistant Professor in 1995 and was promoted to Associate Professor with tenure in 2000. She moved to San Antonio, Texas to work at the University of Texas Health Science Center at San Antonio where she worked in the General Dentistry department as a group practice leader until 2006. She moved back to UF in 2006 as an Associate Professor and was granted tenure again in 2009. She currently works in the Department of Restorative Dental Sciences in the Division of Prosthodontics.

Dr. Esquivel-Upshaw is an active member of the American Association of Dental Research, International Association of Dental Research and the American College of Prosthodontists. She is a journal reviewer for several dental journals including Dental Materials and the Journal of Prosthodontics to name a few. Her patient care activities include fixed and removable denture prostheses mainly for clinical research.

Specialties
  • Dentistry
Areas of Interest
  • Bridges
  • Dental Fillings
  • Dental Implants
  • Dental crowns

Research Profile

Dr. Esquivel-Upshaw is heavily involved with research. She has over thirty peer-reviewed publications in high impact journals, several book chapters in dental textbooks and scientific abstracts. She has obtained funding both from NIH and industry. Her research areas of interest include ceramics, dental materials, wear of enamel, and clinical research. She conducts treatment of patients in the College of Dentistry’s Dental Clinical Research Unit, which is affiliated with the CTSI. She currently has collaborations with Chemical Engineering, Materials Science Engineering and IFAS.

Open Researcher and Contributor ID (ORCID)

0000-0003-3642-8087

Publications

Academic Articles
2024
High sensitivity saliva-based biosensor in detection of breast cancer biomarkers: HER2 and CA15-3
Journal of Vacuum Science & Technology B. 42(2) [DOI] 10.1116/6.0003370. [PMID] 38362284.
2024
Impact of Silicon Carbide Coating and Nanotube Diameter on the Antibacterial Properties of Nanostructured Titanium Surfaces
Materials. 17(15) [DOI] 10.3390/ma17153843. [PMID] 39124507.
2024
Osteoblast Growth in Quaternized Silicon Carbon Nitride Coatings for Dental Implants
Materials. 17(21) [DOI] 10.3390/ma17215392. [PMID] 39517666.
2024
Sensitive Detection of Oral Leukoplakia: Analyzing P90 Biomarkers in Saliva and Tissue
Biosensors. 14(6) [DOI] 10.3390/bios14060281. [PMID] 38920585.
2023
Enhancing the Hydrophobicity and Antibacterial Properties of SiCN-Coated Surfaces with Quaternization to Address Peri-Implantitis
Materials. 16(17) [DOI] 10.3390/ma16175751. [PMID] 37687444.
2023
Evaluation of dry stored disposable sensor strip on rapid SARS-CoV-2 detection platform
Journal of Vacuum Science & Technology B. 41(1) [DOI] 10.1116/6.0002293.
2023
High sensitivity CIP2A detection for oral cancer using a rapid transistor-based biosensor module.
Journal of vacuum science and technology. B, Nanotechnology & microelectronics : materials, processing, measurement, & phenomena : JVST B. 41(1) [DOI] 10.1116/6.0002175. [PMID] 36531804.
2023
Proof testing to improve the reliability and lifetime of ceramic dental prostheses.
Dental materials : official publication of the Academy of Dental Materials. 39(2):227-234 [DOI] 10.1016/j.dental.2023.01.004. [PMID] 36707313.
2023
Properties of SiCN Films Relevant to Dental Implant Applications
Materials. 16(15) [DOI] 10.3390/ma16155318. [PMID] 37570022.
2022
Color perceptibility and validity of silicon carbide-based protective coatings for dental ceramics.
The Journal of prosthetic dentistry. 127(6):918-924 [DOI] 10.1016/j.prosdent.2020.10.023. [PMID] 33483139.
2022
Digital biosensor for human cerebrospinal fluid detection with single-use sensing strips.
Journal of vacuum science and technology. B, Nanotechnology & microelectronics : materials, processing, measurement, & phenomena : JVST B. 40(2) [DOI] 10.1116/6.0001576. [PMID] 36032198.
2022
Effect of Silicon Carbide Coating on Osteoblast Mineralization of Anodized Titanium Surfaces
Journal of Functional Biomaterials. 13(4) [DOI] 10.3390/jfb13040247. [PMID] 36412888.
2022
Finite Element Analysis of an Implant-Supported FDP with Different Connector Heights
Symmetry. 14(11) [DOI] 10.3390/sym14112334.
2022
Fracture of Lithia Disilicate Ceramics under Different Environmental Conditions
Materials. 15(15) [DOI] 10.3390/ma15155261. [PMID] 35955196.
2022
Rapid SARS-CoV-2 diagnosis using disposable strips and a metal-oxide-semiconductor field-effect transistor platform.
Journal of vacuum science and technology. B, Nanotechnology & microelectronics : materials, processing, measurement, & phenomena : JVST B. 40(2) [DOI] 10.1116/6.0001615. [PMID] 36032199.
2022
The Effect of Amino Sugars on the Composition and Metabolism of a Microcosm Biofilm and the Cariogenic Potential against Teeth and Dental Materials
Journal of Functional Biomaterials. 13(4) [DOI] 10.3390/jfb13040223. [PMID] 36412864.
2022
Three-Dimensional Finite Element Analysis of Different Connector Designs for All-Ceramic Implant-Supported Fixed Dental Prostheses
Ceramics. 5(1):34-43 [DOI] 10.3390/ceramics5010004.
2021
Fast SARS-CoV-2 virus detection using disposable cartridge strips and a semiconductor-based biosensor platform
Journal of Vacuum Science & Technology B, Nanotechnology and Microelectronics: Materials, Processing, Measurement, and Phenomena. 39(3) [DOI] 10.1116/6.0001060. [PMID] 34055475.
2021
Forensic and reliability analyses of fixed dental prostheses
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 109(9):1360-1368 [DOI] 10.1002/jbm.b.34796. [PMID] 33527747.
2021
In Vitro Corrosion of SiC-Coated Anodized Ti Nano-Tubular Surfaces
Journal of Functional Biomaterials. 12(3) [DOI] 10.3390/jfb12030052. [PMID] 34564201.
2021
Nanostructured Surfaces to Promote Osteoblast Proliferation and Minimize Bacterial Adhesion on Titanium
Materials. 14(16) [DOI] 10.3390/ma14164357. [PMID] 34442878.
2021
Novel Coatings to Minimize Corrosion of Titanium in Oral Biofilm
Materials. 14(2) [DOI] 10.3390/ma14020342. [PMID] 33445481.
2021
Qualitative Analysis of Remineralization Capabilities of Bioactive Glass (NovaMin) and Fluoride on Hydroxyapatite (HA) Discs: An In Vitro Study
Materials. 14(14) [DOI] 10.3390/ma14143813. [PMID] 34300732.
2021
Three-Dimensional Finite Element Analysis of the Veneer—Framework Thickness in an All-Ceramic Implant Supported Fixed Partial Denture
Ceramics. 4(2):199-207 [DOI] 10.3390/ceramics4020015.
2020
Annealing and N2 Plasma Treatment to Minimize Corrosion of SiC-Coated Glass-Ceramics.
Materials (Basel, Switzerland). 13(10) [DOI] 10.3390/ma13102375. [PMID] 32455653.
2020
Anti-Bacterial Properties and Biocompatibility of Novel SiC Coating for Dental Ceramic.
Journal of functional biomaterials. 11(2) [DOI] 10.3390/jfb11020033. [PMID] 32443691.
2020
Demonstration of a SiC Protective Coating for Titanium Implants
Materials. 13(15) [DOI] 10.3390/ma13153321. [PMID] 32722625.
2020
Dissolution activation energy of a fluorapatite glass-ceramic veneer for dental applications.
Materials science & engineering. C, Materials for biological applications. 111 [DOI] 10.1016/j.msec.2020.110802. [PMID] 32279806.
2020
Effect of pH Cycling Frequency on Glass–Ceramic Corrosion
Materials. 13(16) [DOI] 10.3390/ma13163655. [PMID] 32824815.
2020
Factors influencing the survival of implant-supported ceramic-ceramic prostheses: A randomized, controlled clinical trial
Journal of Dentistry. 103 [DOI] 10.1016/j.jjodo.2020.100017. [PMID] 34059304.
2020
Finite Element Analysis (FEA) of Palatal Coverage on Implant Retained Maxillary Overdentures
Applied Sciences. 10(19) [DOI] 10.3390/app10196635.
2020
Hydroxyapatite Formation on Coated Titanium Implants Submerged in Simulated Body Fluid
Materials. 13(24) [DOI] 10.3390/ma13245593. [PMID] 33302431.
2020
Novel Coating to Minimize Corrosion of Glass-Ceramics for Dental Applications.
Materials (Basel, Switzerland). 13(5) [DOI] 10.3390/ma13051215. [PMID] 32182716.
2020
Novel Coatings to Minimize Bacterial Adhesion and Promote Osteoblast Activity for Titanium Implants.
Journal of functional biomaterials. 11(2) [DOI] 10.3390/jfb11020042. [PMID] 32560139.
2020
Novel methodology for measuring intraoral wear in enamel and dental restorative materials
Clinical and Experimental Dental Research. 6(6):677-685 [DOI] 10.1002/cre2.322. [PMID] 32955159.
2020
Retrospective analysis of survival rates of post-and-cores in a dental school setting.
The Journal of prosthetic dentistry. 123(3):434-441 [DOI] 10.1016/j.prosdent.2019.05.003. [PMID] 31353108.
2020
The Galvanic Effect of Titanium and Amalgam in the Oral Environment
Materials. 13(19) [DOI] 10.3390/ma13194425. [PMID] 33027910.
2020
Titanium Corrosion in Peri-Implantitis
Materials. 13(23) [DOI] 10.3390/ma13235488. [PMID] 33276474.
2019
Antibacterial Properties of Charged TiN Surfaces for Dental Implant Application
ChemistrySelect. 4(31):9185-9189 [DOI] 10.1002/slct.201901001. [PMID] 32149184.
2019
Comprehensive analysis of laserscanner validity used for measurement of wear
Journal of Oral Rehabilitation. 46(6):503-510 [DOI] 10.1111/joor.12778. [PMID] 30759313.
2019
Cover Image
Journal of Oral Rehabilitation. 46(6) [DOI] 10.1111/joor.12792.
2019
Demonstration of SiO2/SiC‐based protective coating for dental ceramic prostheses
Journal of the American Ceramic Society. 102(11):6591-6599 [DOI] 10.1111/jace.16525. [PMID] 31819280.
2019
Effect of carbamide peroxide bleaching on enamel characteristics and susceptibility to further discoloration.
The Journal of prosthetic dentistry. 121(2):340-346 [DOI] 10.1016/j.prosdent.2018.03.006. [PMID] 30139674.
2018
Novel Testing for Corrosion of Glass-Ceramics for Dental Applications.
Journal of dental research. 97(3):296-302 [DOI] 10.1177/0022034517732283. [PMID] 28922616.
2018
Randomized clinical study of wear of enamel antagonists against polished monolithic zirconia crowns.
Journal of dentistry. 68:19-27 [DOI] 10.1016/j.jdent.2017.10.005. [PMID] 29042241.
2015
Peri-implant complications for posterior endosteal implants.
Clinical oral implants research. 26(12):1390-6 [DOI] 10.1111/clr.12484. [PMID] 25263400.
2014
Fracture analysis of randomized implant-supported fixed dental prostheses.
Journal of dentistry. 42(10):1335-42 [DOI] 10.1016/j.jdent.2014.07.001. [PMID] 25016139.
2014
Randomized clinical trial of implant-supported ceramic-ceramic and metal-ceramic fixed dental prostheses: preliminary results.
Journal of prosthodontics : official journal of the American College of Prosthodontists. 23(2):73-82 [DOI] 10.1111/jopr.12066. [PMID] 23758092.
2013
Randomized, controlled clinical trial of bilayer ceramic and metal-ceramic crown performance.
Journal of prosthodontics : official journal of the American College of Prosthodontists. 22(3):166-73 [DOI] 10.1111/j.1532-849X.2012.00913.x. [PMID] 22978697.
2013
Surface degradation of dental ceramics as a function of environmental pH.
Journal of dental research. 92(5):467-71 [DOI] 10.1177/0022034513484332. [PMID] 23569159.
2013
Time-Dependent Fracture Probability of Bilayer, Lithium-Disilicate-Based, Glass-Ceramic, Molar Crowns as a Function of Core/Veneer Thickness Ratio and Load Orientation
Dental Materials. 29:1132-1138 [DOI] 10.1016/j.dental.7013.08.206.
2013
Time-dependent fracture probability of bilayer, lithium-disilicate-based, glass-ceramic, molar crowns as a function of core/veneer thickness ratio and load orientation.
Dental materials : official publication of the Academy of Dental Materials. 29(11):1132-8 [DOI] 10.1016/j.dental.2013.08.206. [PMID] 24060349.
2012
Three years in vivo wear: core-ceramic, veneers, and enamel antagonists.
Dental materials : official publication of the Academy of Dental Materials. 28(6):615-21 [DOI] 10.1016/j.dental.2012.02.001. [PMID] 22410113.
2011
Comparative reliability analyses of zirconium oxide and lithium disilicate restorations in vitro and in vivo.
Journal of the American Dental Association (1939). 142 Suppl 2:4S-9S [PMID] 21454834.
2008
Four-year clinical performance of a lithia disilicate-based core ceramic for posterior fixed partial dentures.
The International journal of prosthodontics. 21(2):155-60 [PMID] 18546772.
2006
In vivo wear of enamel by a lithia disilicate-based core ceramic used for posterior fixed partial dentures: first-year results.
The International journal of prosthodontics. 19(4):391-6 [PMID] 16900824.
2004
Clinical performance of a lithia disilicate-based core ceramic for three-unit posterior FPDs.
The International journal of prosthodontics. 17(4):469-75 [PMID] 15382785.
2003
Surface treatments to improve bond strength in removable partial dentures.
General dentistry. 51(5):402-4 [PMID] 15055627.
2002
Maximum clenching force of patients with moderate loss of posterior tooth support: a pilot study.
The Journal of prosthetic dentistry. 88(5):498-502 [PMID] 12473999.
2001
Fracture resistance of all-ceramic and metal-ceramic inlays.
The International journal of prosthodontics. 14(2):109-14 [PMID] 11843445.
2001
Resistance to staining, flexural strength, and chemical solubility of core porcelains for all-ceramic crowns.
The International journal of prosthodontics. 14(3):284-8 [PMID] 11484579.
2000
Assessment of MEDLINE search strategies for randomized controlled trials in prosthodontics.
Journal of prosthodontics : official journal of the American College of Prosthodontists. 9(1):8-13 [PMID] 11074022.
2000
Ceramic design concepts based on stress distribution analysis.
Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995). 21(8):649-52, 654; quiz 656 [PMID] 11199655.
1999
Developing a register for randomized controlled trials in prosthodontics: results of a search from prosthodontic journals published in the United States.
The Journal of prosthetic dentistry. 82(6):699-703 [PMID] 10588806.

Grants

Sep 2024 ACTIVE
Temperature changes and inflammatory response in pulpal and gingival tissues surrounding dental restorative treatments performed using blue and red wavelengths: an in vivo and ex vivo study
Role: Other
Funding: NATL INST OF HLTH NIDCR
Sep 2022 – Aug 2024
Novel?coated?nanostructured implant surfaces to increase osseointegration and decrease peri-implantitis in a physiologic rat model
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDCR
Jan 2022 – Apr 2022
Analytical specificity of COVID-19 biosensor
Role: Principal Investigator
Funding: HOUNDSTOOTHE ANALYTICS
Feb 2021 – Feb 2023
Risk factors associated with the prevalence of Peri-Implantitis disease
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDCR
Aug 2020 – Jul 2023
MRI: Acquisition of Nano-resolution Zeiss Xradia 620 Versa X-ray Computed Tomography with Phase Contrast and Lab Diffraction Contrast Tomography
Role: Other
Funding: NATL SCIENCE FOU
Apr 2017 – Jun 2021
OoR CTSI Institutional Matching Support
Role: Project Manager
Funding: UF DIV OF SPONSORED RES MATCHING FUNDS
Jun 2016 – Sep 2021
Novel coatings to minimize surface degradation and fracture susceptibility of dental ceramics
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDCR
Jun 2016 – May 2019
OR-DRPD-ROF2016:Novel coating to minimize bacterial adhesions and tooth wear in denture acrylic
Role: Principal Investigator
Funding: UF RESEARCH
Jan 2013 – Dec 2018
Wear of Enamel Antagonists by Polished Ceramic Surfaces
Role: Principal Investigator
Funding: 3M COMPANY

Contact Details

Phones:
Business:
(352) 273-5850
Emails:
Addresses:
Business Mailing:
D9-6
1395 CENTER DR
PO BOX 100435
GAINESVILLE FL 326103006
Business Street:
1600 SW ARCHER RD
GAINESVILLE FL 32610